Find the "culprit" that diabetic pain

A group of British scientists have found the cause of the increased sensitivity to pain and temperature of the patient with diabetes, a promising new treatment for the side effects of diabetes road.

Previously, glucose metabolism abnormalities occur causes more pain yet to be clearly explained. So far the research team, said the compound methylglyoxal (MG) ​​is overproduction of glucose in diabetes, a new culprit causing pain and discomfort.

Professor Paul Thornalley

"MG appear and attack and alter an important protein in neurons called" Nav1.8 "nerves causing problems with high sensitivity painful wounds and extreme temperatures. So diabetics often severe pain when hot and cold temperature changes, "Professor Paul Thornalley, a co-author of the study from the University of Warwick, United Kingdom said.

With this discovery, research has shown to reduce pain by removing MG and opens the way effective drug therapy for patients with diabetes. Researchers at Warwick currently investigating ways to increase the amount of an enzyme called Glo1, to remove catalyst MG.

Reportedly, stock painful illness usually occurs pee unusual and prolonged pain for approximately 50% of patients, affecting sleep, mood, walking, work of the patient.